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Rabies Vaccine?
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According to the CDC website, Rabies Vaccine is recommended for travelers to Zimbabwe " for travelers spending a lot of time outdoors, especially in rural areas, involved in activities such as bicycling, camping, or hiking. Also recommended for travelers with significant occupational risks (such as veterinarians), for long-term travelers and expatriates living in areas with a significant risk of exposure, and for travelers involved in any activities that might bring them into direct contact with bats, carnivores, and other mammals."
For people going on a DG safari of 10-14 days, is the consensus that the vaccination is needed or not?
 
Posts: 156 | Registered: 06 May 2010Reply With Quote
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Its was recomended when I went to RSA also never had it and most just laugh when I mentioned it. I guess it would not be funny if you got bit but I am guessing its not a priority.
 
Posts: 97 | Location: USA Massachusetts | Registered: 03 March 2010Reply With Quote
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I just visited my travel medicine clinic last week. No rabies or yellow fever vaccines given. They set me up with shots for Hepatitis A & B,and tetanus, a seires of live virus capsules for typhoid, and a prescription of Malarone for malaria prevention.
 
Posts: 262 | Location: Mount Pleasant, SC | Registered: 02 February 2010Reply With Quote
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That exact recomendation is given for just about every African country I have visisted. The only time I remotely considered it was when there was an outbreak of rabies in kudu in Namibia, but I didn't opt to have the vaccine and the nurses at the travel clinic were not at all pushy about it.


"...Africa. I love it, and there is no reason for me to explore why. She affects some people that way, and those who feel as I do need no explanation." from The Last Safari
 
Posts: 839 | Location: Greensboro, Georgia USA | Registered: 17 July 2004Reply With Quote
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I got it mostly because as hunters we're exposed to things at home as well as abroad, I figured it couldn't hurt. I actually had a friend who went through rabies treatment and after he described it I figured I'd rather have the vaccine than the treatment.
 
Posts: 2763 | Registered: 11 March 2004Reply With Quote
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The rabies vaccination is the same biologic and three injection regimen used for treatment of a suspected rabid bite. Since there is a very low probability of being exposed, the military docs here strongly recommended not taking it unless exposure was suspected.


"Cleverly disguised as a responsible adult."
 
Posts: 1313 | Location: The People's Republic of Maryland, USA | Registered: 05 August 2006Reply With Quote
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I got the shots after talking with my nephew who is a DVM; I was spending a lot of time in Africa and took everything, including polio update.


Mike
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Posts: 3577 | Location: Silicon Valley | Registered: 19 November 2008Reply With Quote
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You would be very unlucky to contract Rabies while travelling. The people who do are the careless 'tourist' types who insist on stopping and feeding semi-tame animals and then get bitten when they withdraw food.

If any animal (like a spring hare) in Africa acts strangely with 'bizarre' behaviour, then it is suspect of rabies.
 
Posts: 1433 | Location: Australia | Registered: 21 March 2008Reply With Quote
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Just so you know, if indeed you get the rabies vaccination, and you get exposed, you still have to get the follow up treatment within the 10 day time frame.

The vaccine isn't that useful for that reason. It doesn't prevent you from getting rabies~





 
Posts: 732 | Location: Texas | Registered: 05 October 2009Reply With Quote
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The pre-exposure vaccine is for if you get exposed to a rabid animal and don't know it.

If you get exposed to a known rabid animal, you will still have to undero the post-exposure vaccine protocol.

Your choice.
 
Posts: 2921 | Location: Canada | Registered: 07 March 2001Reply With Quote
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quote:
Originally posted by Oryxhunter1983:
Just so you know, if indeed you get the rabies vaccination, and you get exposed, you still have to get the follow up treatment within the 10 day time frame.

The vaccine isn't that useful for that reason. It doesn't prevent you from getting rabies~


I could be wrong...but I believe it is true...that there has NEVER been a documented case of rabies in an animal or man who has even received one rabies vaccination. It is a very GOOD vaccine.

If you are vaccinated...and you get exposed...they now usually check your titers...and if good...nothing further.

I have been exposed to rabies several times in my carreer. Been vacinated since early 80's with a booster every 3-4 years. Never gotten a follow up series...titer always good.

But...unless you go into bat caves...unlikely to be exposed and not know it.


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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Folks,

Just get whatever the CDC recommends. To do anything else is playing Russian roulete with your health. Be smart!

Mark


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Posts: 13088 | Location: LAS VEGAS, NV USA | Registered: 04 August 2002Reply With Quote
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quote:
Originally posted by MARK H. YOUNG:
Folks,

Just get whatever the CDC recommends. To do anything else is playing Russian roulete with your health. Be smart!

Mark


tu2 Besides the rabies vaccine is one of the nicer ones!


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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Lane,

Taken from the CDC website...

http://www.cdc.gov/vaccines/pu...loads/vis-rabies.pdf


"A person who is exposed and has never been vaccinated against rabies should get 4 doses of rabies vaccine - one dose right away, and additional doses on the 3rd, 7th, and 14th days. They should also get another shot called Rabies Immune Globulin at the same time as the first dose.

A person who has been previously vaccinated should get 2 doses of rabies vaccine - one right away and another on the 3rd day. Rabies Immune Globulin is not needed."

So we are both kinda correct...it's not the end all!





 
Posts: 732 | Location: Texas | Registered: 05 October 2009Reply With Quote
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I would get the vaccine.

First, CDC recommendations are usually based on some level of fact, not internet medicine.

Second, the comment on the vaccine vs the immune globulin- I have administered the rabies IgG and it is one of the most painful injections one can give. You first determine a dose based on weight, then you are supposed to (if possible) give half of it in the wound site- not too bad for a kid (volume and their tissue is pretty elastic), but not pleasant for an adult (for the doc giving it, let alone the patient) Immunoglobulin can cause serum sickness and if its not genetically engineered, it is usually horse sera. In the US, horse is a nonissue, but I don't know what it may be like in Zim. The remainder goes in IM elsewhere (usually your rump.) This is supposed to be given within 24 hours of exposure, but they will do it whenever you arrive as that is what is recommended. You also get the series of 4 shots, which are no longer the nasty stomach ones (if they ever did such a thing, that was before my time, but I heard about it.) The new vaccine is a genetically engineered vaccine that has no risk of giving you rabies (but then its not risk free for other things)

The third reason to get it is that you may not know if you have been bitten. The last statistics I saw were that most rabies fatalities in the US ended up being from unknown untreated bat bites.

Talk with your regular doc or someone who knows what your health history is AND what you are doing. My experience with travel clinics is they do just what some of you do- pull up the CDC recommendations and give whatever they say unless you object to it. The needs of someone going in to the bush of Zimbabwe are a lot different than the guy who is doing a photosafari in Kruger in SA. The travel clinic may be the only place you can get the shots, but your regular doc can guide you with personal advice based on your history.
 
Posts: 11198 | Location: Minnesota USA | Registered: 15 June 2007Reply With Quote
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I am a 51 yr old doctor-I looked at the pros and cons for just the scenario you discuss and got myself vaccinated.Since I safari every few years I get it topped up with a booster a few weeks before I return to Africa.I suggest you do the same.


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The wide brown land for me!
 
Posts: 302 | Location: Australia | Registered: 09 February 2005Reply With Quote
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Thank you to all who have made suggestions. Since the opinions vary so much, will plan to speak with an Infectious Disease Specialist and see what their official recommendation is.
 
Posts: 156 | Registered: 06 May 2010Reply With Quote
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quote:
Originally posted by Oryxhunter1983:
Lane,

Taken from the CDC website...

http://www.cdc.gov/vaccines/pu...loads/vis-rabies.pdf

"A person who is exposed and has never been vaccinated against rabies should get 4 doses of rabies vaccine - one dose right away, and additional doses on the 3rd, 7th, and 14th days. They should also get another shot called Rabies Immune Globulin at the same time as the first dose.

A person who has been previously vaccinated should get 2 doses of rabies vaccine - one right away and another on the 3rd day. Rabies Immune Globulin is not needed."

So we are both kinda correct...it's not the end all!


The rest-of-the-story...unless your titer is high (which it will be 90+% of the time from vacc) then...NADA!!!

BTW...it is the immunoglobulin in which you would rather AVOID. CRYBABY


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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quote:
Originally posted by crbutler:
I would get the vaccine.

First, CDC recommendations are usually based on some level of fact, not internet medicine.

Second, the comment on the vaccine vs the immune globulin- I have administered the rabies IgG and it is one of the most painful injections one can give. You first determine a dose based on weight, then you are supposed to (if possible) give half of it in the wound site- not too bad for a kid (volume and their tissue is pretty elastic), but not pleasant for an adult (for the doc giving it, let alone the patient) Immunoglobulin can cause serum sickness and if its not genetically engineered, it is usually horse sera. In the US, horse is a nonissue, but I don't know what it may be like in Zim. The remainder goes in IM elsewhere (usually your rump.) This is supposed to be given within 24 hours of exposure, but they will do it whenever you arrive as that is what is recommended. You also get the series of 4 shots, which are no longer the nasty stomach ones (if they ever did such a thing, that was before my time, but I heard about it.) The new vaccine is a genetically engineered vaccine that has no risk of giving you rabies (but then its not risk free for other things)

The third reason to get it is that you may not know if you have been bitten. The last statistics I saw were that most rabies fatalities in the US ended up being from unknown untreated bat bites.

Talk with your regular doc or someone who knows what your health history is AND what you are doing. My experience with travel clinics is they do just what some of you do- pull up the CDC recommendations and give whatever they say unless you object to it. The needs of someone going in to the bush of Zimbabwe are a lot different than the guy who is doing a photosafari in Kruger in SA. The travel clinic may be the only place you can get the shots, but your regular doc can guide you with personal advice based on your history.


tu2


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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The travel clinic I use is at Michigan State University...a place with a pretty well known vet med program. I was encouraged to get the rabies vaccine. They explained to me that if for instance I was bit by an animal I would probably be smart enough to seek out a rabies treatment; the risk that concerned them was that I unknowingly came into contact with an infected animal I could potentially delay rabies treatment until it was too late.

It is my understanding that there occasional rabies outbreaks in some African big game animals.

405wcf
 
Posts: 121 | Registered: 12 July 2009Reply With Quote
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I am a big proponent of vaccinations. I usually accept the cdc recomendations without question. Rabies is the only one I took a pass on. I figure unless I am in an area known to have heavy outbreaks the risk is no greater than normal. It would still be prudent to prevent if you could. The series of three shots just buys time if somehow you didnt know you were exposed. You still have to complete ther series and get the damn globulin shot. That is the one that is like shooting maple syrup and hurts like hell. As long as you are going to somplace civilized like RSA I figure it probably isnt an issue. Still, an ounce of prevention...


Happiness is a warm gun
 
Posts: 4106 | Location: USA | Registered: 06 March 2002Reply With Quote
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quote:
Originally posted by Mike Smith:
I am a big proponent of vaccinations. I usually accept the cdc recomendations without question. Rabies is the only one I took a pass on. I figure unless I am in an area known to have heavy outbreaks the risk is no greater than normal. It would still be prudent to prevent if you could. The series of three shots just buys time if somehow you didnt know you were exposed. You still have to complete ther series and get the damn globulin shot. That is the one that is like shooting maple syrup and hurts like hell. As long as you are going to somplace civilized like RSA I figure it probably isnt an issue. Still, an ounce of prevention...


Wrong...read above!


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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In July, 2009 in Luke Samaras's camp up in Maasailand, I was wishing I had. A rabid honey badger spent a very long five minutes trying to break into my tent. I was up on the bed with my rifle and flashlight, not knowing what the hell was out there so mad at me. He finally gave up and ran over to the staff area and attacked my assistant tracker and another guy in their sleep before somebody killed him with a panga. That was after their tent collapsed and they had this evil bastard in there with them. Very nasty business and in no way funny. Rama got chewed up pretty good.

The guys had to drive three hours into Arusha to get shots. So there is a threat, no matter how statistically minor it might be.
 
Posts: 11729 | Location: Florida | Registered: 25 October 2006Reply With Quote
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quote:
Originally posted by jetdrvr:
In July, 2009 in Luke Samaras's camp up in Maasailand, I was wishing I had. A rabid honey badger spent a very long five minutes trying to break into my tent. I was up on the bed with my rifle and flashlight, not knowing what the hell was out there so mad at me. He finally gave up and ran over to the staff area and attacked my assistant tracker and another guy in their sleep before somebody killed him with a panga. That was after their tent collapsed and they had this evil bastard in there with them. Very nasty business and in no way funny. Rama got chewed up pretty good.

The guys had to drive three hours into Arusha to get shots. So there is a threat, no matter how statistically minor it might be.


Animals like Kudu commonly get rabies as well and don't show "classic" rabies-like signs. Some just dull-depressed.

Could easily shoot one and get exposed.


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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ledvm - Are you authorized to give rabies shots to us hunters going abroad?? Wink Can hardly wait for your answer!! dancing

Larry Sellers
SCI Life Member



quote:
Originally posted by ledvm:
quote:
Originally posted by jetdrvr:
In July, 2009 in Luke Samaras's camp up in Maasailand, I was wishing I had. A rabid honey badger spent a very long five minutes trying to break into my tent. I was up on the bed with my rifle and flashlight, not knowing what the hell was out there so mad at me. He finally gave up and ran over to the staff area and attacked my assistant tracker and another guy in their sleep before somebody killed him with a panga. That was after their tent collapsed and they had this evil bastard in there with them. Very nasty business and in no way funny. Rama got chewed up pretty good.

The guys had to drive three hours into Arusha to get shots. So there is a threat, no matter how statistically minor it might be.


Animals like Kudu commonly get rabies as well and don't show "classic" rabies-like signs. Some just dull-depressed.

Could easily shoot one and get exposed.
 
Posts: 3460 | Location: Jemez Mountains, New Mexico | Registered: 09 February 2006Reply With Quote
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quote:
Originally posted by Larry Sellers:
ledvm - Are you authorized to give rabies shots to us hunters going abroad?? Wink Can hardly wait for your answer!! dancing

Larry Sellers
SCI Life Member



quote:
Originally posted by ledvm:
quote:
Originally posted by jetdrvr:
In July, 2009 in Luke Samaras's camp up in Maasailand, I was wishing I had. A rabid honey badger spent a very long five minutes trying to break into my tent. I was up on the bed with my rifle and flashlight, not knowing what the hell was out there so mad at me. He finally gave up and ran over to the staff area and attacked my assistant tracker and another guy in their sleep before somebody killed him with a panga. That was after their tent collapsed and they had this evil bastard in there with them. Very nasty business and in no way funny. Rama got chewed up pretty good.

The guys had to drive three hours into Arusha to get shots. So there is a threat, no matter how statistically minor it might be.


Animals like Kudu commonly get rabies as well and don't show "classic" rabies-like signs. Some just dull-depressed.

Could easily shoot one and get exposed.


Nope...are you??? I do give myself and my associates our boosters every 3 years. And...I bet I know more about rabies...its transmission...and its epidemiology than anyone who has given you yours my friend. Wink Wink Wink

Besides what I learned in vet school...I have been seriously exposed 3 times in my career. That...makes you do your home work. tu2

Besides...people bitch too much when stuck. Smiler


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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quote:
Originally posted by Edod:
Thank you to all who have made suggestions. Since the opinions vary so much, will plan to speak with an Infectious Disease Specialist and see what their official recommendation is.


And all he will do is parrot the CDC recommendations and interject his bias into your discussion.

As a former owner and medical director of a travel medicine clinic, ask me how I know. Wink

Vaccinations for international travel are more akin to insurance than medicine. Only you can determine if the risk/reward is worth it to you.

In the US, the only folks that are regularly vaccinated for rabies are vets and those that work with them for obvious reasons.

Travel to the wilds of Africa carries with it a risk of exposure to a rabid animal. Common sense can lessen the risk of contact, but not eliminate it.



So, you gotta ask yourself.

Big Grin


Hunting: Exercising dominion over creation at 2800 fps.
 
Posts: 3113 | Location: Southern US | Registered: 21 July 2002Reply With Quote
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I have a licence if you have the meds. and a doc's orders for it Big Grin
 
Posts: 3818 | Location: kenya, tanzania,RSA,Uganda or Ethophia depending on day of the week | Registered: 27 May 2009Reply With Quote
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Ledvm:

We could have a debate here, but with respect to whether you are qualified to give me the vaccination -- I'm a lawyer and tend to debate the point -- most people I know tend to think I'm a son a bitch -- so shouldn't you be totally authorized to give me the shot? Just askin'
 
Posts: 10483 | Location: Houston, Texas | Registered: 26 December 2005Reply With Quote
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I here-by give authority to DrHook to give rabies vaccine under my medical license in this state to anyone I know going to Africa. I'm not a son of a bitch, but I get called that frequently. Hook must speak for himself.
Lavaca is a town close down the road, also a beef-cow, depending on who your're a talkin' to.


Steve
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Posts: 8100 | Location: NW Arkansas | Registered: 09 July 2005Reply With Quote
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Ledvm, Yes I mispoke about the globulin shot. Still unless you are going somewhere very remote or are possibly exposed day in and day out for a long period of time, I question the recommendation.


Happiness is a warm gun
 
Posts: 4106 | Location: USA | Registered: 06 March 2002Reply With Quote
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Mr. Smith,

With all due respect, do you have any background to question it? There have been veterinarians and physicians who both think its reasonable, and prudent to do so and have done so themselves.

I would hope that your physician educated you about it, and then you made a decision that FOR YOU it was not a good idea. That is not necessarily a medical decision, but could be religious, economic, or just plain fear of vaccination.

In any case, unless you want to provide us with a reason to question the recommendation, it might be wise to just not say something like that.
 
Posts: 11198 | Location: Minnesota USA | Registered: 15 June 2007Reply With Quote
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quote:
Originally posted by lavaca:
Ledvm:

We could have a debate here, but with respect to whether you are qualified to give me the vaccination -- I'm a lawyer and tend to debate the point -- most people I know tend to think I'm a son a bitch -- so shouldn't you be totally authorized to give me the shot? Just askin'


Because a veterinarian can't prescribe to people.
 
Posts: 11198 | Location: Minnesota USA | Registered: 15 June 2007Reply With Quote
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Actually I do have a medical background and am certified to give most vaccinations in Ohio. I also admit to being unable to work at the moment because of some neurological problems that are playing hell with my memory and at times causing me confusion. I will openly apologize and correct any statement that I might inadvertantly make as a result of that. Not that I really owed you an explanation as such I thought it might put things in better perspective. You dont realize how difficult making the decision to out myself as it were was. Now, back to the subject. If you look at my first post you will see I am a proponent not a detractor of vaccinations. I dont fell the risk is any higher for most of us going on a 10 to 14 day trip to hunt most (not all) places in Africa then we are here if you spend any time outdoors. I weigh the risks and decided as such that rabies and anthrax (not that it is available) were not warranted for places like RSA, Namibia, Zim etc for a short hunting trip.


Happiness is a warm gun
 
Posts: 4106 | Location: USA | Registered: 06 March 2002Reply With Quote
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Get the vaccine. There are a lot of stray animals on the continent and that is what you are concerned about....and no, you don't have to be an idiot to be bitten by a stray dog or cat that you are shooing out of the camp or your room. Wanna ask me how I know?

Now, that said, my understanding is that the vaccine will NOT 100% guarantee that you won't get rabies and I believe you MAY still have to seek treatment if it has been a while since you were vaccinated and you need a booster (ledvm, can you please clarify how this works?). However, if you are exposed, and don't have the vaccine, the odds of you actually getting rabies increase the longer you wait to get the first shot in the series to prevent the disease. Wait a few days, a week, or more and your chances of becoming symptomatic increase more than without the vaccine. Do you really want to be wandering around Zim hospitals panicked because you can't find the right shot within a few days and your odds of becoming symptomatic just increased by X%? Rabies is very nearly 100% fatal remember, is not a pleasant way to die, and if do you survive it, you will almost assuredly wish you were dead from what I understand. If you have the vaccine you may still need to seek treatment, but you won't have to freak out if it is difficult or impossible to find in the area. That peace of mind is worth it....again, ask me how I know.
 
Posts: 2472 | Registered: 06 July 2008Reply With Quote
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quote:
Originally posted by lavaca:
Ledvm:

We could have a debate here, but with respect to whether you are qualified to give me the vaccination -- I'm a lawyer and tend to debate the point -- most people I know tend to think I'm a son a bitch -- so shouldn't you be totally authorized to give me the shot? Just askin'


I thought it was @$$-hole??? And I don't touch those nasty things! rotflmo


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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I have done a cut and paste for the Cliff Notes crowd.

full text here
http://emedicine.medscape.com/article/785543-overview



quote:
Rabies is a viral disease of the central nervous system (CNS); it is one of the oldest and most feared diseases reported in medical literature. Incidence of rabies is widespread throughout the world.


Human rabies cases have been documented on all continents except Australia and the Antarctic. Many cases are unreported (or greatly underreported) in developing countries.


Since 1980, most patients with human rabies in the United States have not had definite exposure through a bite wound, making total understanding of the mechanism of transmission somewhat elusive.


Worldwide, canine rabies variants are still epidemic and a major source of human rabies. The World Health Organization (WHO) in 2004 estimates that as many as 55,000 deaths occur from rabies annually, with 56% in Asia and 44% in Africa.


Although rabies is considered to be a uniformly fatal disease, 3 cases of survival were reported in the 1970s.

Suspicion of rabies is clear when a history of an animal bite is given; however, because a history of an animal bite is obtained in less than one half of US cases, diagnosis is problematic. Presentation of a patient in the rabies prodromal stage without a clear exposure history is so nonspecific and rare that making the diagnosis in the ED is essentially impossible. Rabies progresses over 7-14 days, and the mean time between initial presentation and death is 16.2 days.


The 2 rabies vaccines currently available in the United States are the human diploid cell vaccine (HDCV, Imovax) and purified chick embryo cell vaccine (PCECV, Rabavert). Both are made for intramuscular administration and are equal in efficacy and safety. The vaccine takes 7-10 days to induce an active immune response, with immunity lasting approximately 2 years.


No postexposure vaccine failures in the United States have been reported since HDCV was licensed in 1980.


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Posts: 3113 | Location: Southern US | Registered: 21 July 2002Reply With Quote
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Since 1980, most patients with human rabies in the United States have not had definite exposure through a bite wound, making total understanding of the mechanism of transmission somewhat elusive.


quote:
however, because a history of an animal bite is obtained in less than one half of US cases, diagnosis is problematic. Presentation of a patient in the rabies prodromal stage without a clear exposure history is so nonspecific and rare that making the diagnosis in the ED is essentially impossible.


Big Grin


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
J. Lane Easter, DVM

A born Texan has instilled in his system a mind-set of no retreat or no surrender. I wish everyone the world over had the dominating spirit that motivates Texans.– Billy Clayton, Speaker of the Texas House

No state commands such fierce pride and loyalty. Lesser mortals are pitied for their misfortune in not being born in Texas.— Queen Elizabeth II on her visit to Texas in May, 1991.
 
Posts: 38437 | Location: Gainesville, TX | Registered: 24 December 2006Reply With Quote
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Just to make my position clear. I have no problem with the vaccine. I just dont think the risk of exposure is high for a visiting hunter on a short hunt. Is it prudent? Certainly. Prevention is always better than cure. Levdm, as a vet I would bet your exposure in your job is higher. Now if you all want to live and work in any of several reservations I can name your risk goes up. That is also true for the occasional outbreak of plague as well. My point is simply that what you do, where you do it, and the amount of time exposed are all factors.


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Posts: 4106 | Location: USA | Registered: 06 March 2002Reply With Quote
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For what it is worth, I saw a specialist in ID who does a lot of pre-safari type consultations. Her recommendation was, for my 10 day DG hunt in Zimbabwe, to not take the rabies vaccine. She said the risk of exposure, although real, is very small. I have elected to follow her advise.

Thanks again, to all who have contributed to this thread.
 
Posts: 156 | Registered: 06 May 2010Reply With Quote
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