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Cloning brings back Dire Wolf Login/Join 
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posted
https://www.nytimes.com/2025/0...lf-deextinction.html

I do not support this as a matter of policy.

However, to paraphrase the scene from Jurassic Park, “ He did it. The crazy son of a buck he did it.”
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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Subscription or sign-in required. I don't do either.

Can you quote some of the article? Sounds very interesting.
 
Posts: 7816 | Location: Coeur d' Alene, Idaho, USA | Registered: 08 March 2013Reply With Quote
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Try this link:

https://time.com/7274542/colossal-dire-wolf/

TIME

Apr 7, 2025 8:50 AM ET
The Return of the Dire Wolf


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Degenerate 1:1
1 Then Trump said, "Let Us re-make a Nation in MY Image, after My likeness, to rule over everything in the Nation, and over all the earth itself and every creature that crawls upon it".

Degenerate 1:2
2 Then Trump said, "Vengeance is mine, I will repay on your behalf."

Degenerate 1:3
3 "My Kingdom come, My will be done."

"When fascism comes to America, it will be wrapped in the flag and carrying a cross." - Sinclair Lewis

O.J. Trump aka Trumpism's Founding Farter, aka Farter Martyr.

"Be careful. When a democracy is sick, fascism comes to its bedside, but it is not to inquire about its health." - Albert Camus


 
Posts: 24527 | Location: Rural | Registered: 17 February 2017Reply With Quote
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3 pups have been born.
Romulus, Remus, and Khalessi.

In 2021, a separate team of scientists managed to retrieve DNA from the fossils of dire wolves, which went extinct about 13,000 years ago. With the discovery of additional DNA, the Colossal researchers have now edited 20 genes of gray wolves to imbue the animals with key features of dire wolves. They then created embryos from the edited gray-wolf cells, implanted them in surrogate dog mothers and waited for them to give birth.

The result is three healthy wolves — two males that are 6 months old and one female that is 2 months old, named Romulus, Remus and Khaleesi — that have some traits of dire wolves.
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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Beth Shapiro, the chief scientific officer of Colossal, described the wolf pups as the first successful case of de-extinction. “We’re creating these functional copies of something that used to be alive,” she said in an interview.

The animals will remain in captivity. But the technology that the company has developed could potentially help conserve species that have not yet gone extinct, such as the critically endangered red wolf, which is largely limited to North Carolina.
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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Thanks, guys. Fascinating stuff.
 
Posts: 7816 | Location: Coeur d' Alene, Idaho, USA | Registered: 08 March 2013Reply With Quote
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here's an interesting video:

https://youtu.be/fTDlGSIYvZs?si=gL1o3tXDo7-kxJK5

Meet the White Wolf Pack of Ellesmere Island | White Falcon, White Wolf (Part 2) | BBC Earth

These wolves spend the winter in darkness. They don't hibernate. In summer the sun doesn't set.

https://youtu.be/p-DG1ujof0g?si=QbIoXbXP9SSsot_R

The Largest Falcon in the World | White Falcon, White Wolf (Part 1) | BBC Earth

==============================================

Search question: are the wolves on Ellesmere Island related to dire wolves

Results:

AI Overview
Learn more
No, the Arctic wolves on Ellesmere Island, which are a subspecies of gray wolves, are not closely related to the extinct dire wolves, as genetic studies show they diverged from other canine lineages long ago.

Here's a more detailed explanation:
Dire Wolves: A Distinct Lineage:
Genetic research has revealed that dire wolves (Canis dirus) were not closely related to modern gray wolves (Canis lupus). Instead, they represent a distinct lineage that split off from other canids, including gray wolves, much earlier in evolutionary history, around 5.7 million years ago.

Arctic Wolves: A Subspecies of Gray Wolves:
The wolves found on Ellesmere Island, also known as Arctic wolves or white wolves, are a subspecies of gray wolf (Canis lupus arctos). They are closely related to other gray wolf populations found across North America and Eurasia.

Morphological Similarities:
While dire wolves and gray wolves share some morphological similarities, like their wolf-like appearance, genetic evidence indicates that these similarities are due to convergent evolution, where different species evolve similar traits in response to similar environmental pressures, rather than a close evolutionary relationship.

Geographic Isolation:
The dire wolf lineage evolved in the Americas and experienced a long period of geographic isolation, which allowed them to develop into a distinct species.

Implications:
The findings about dire wolves challenge the long-held belief that they were simply larger cousins of gray wolves. They were, in fact, a unique and ancient lineage of canids that went extinct.

=========================================================

https://pmc.ncbi.nlm.nih.gov/articles/PMC7317801/
Ancient DNA suggests modern wolves trace their origin to a Late Pleistocene expansion from Beringia

========================================================

https://en.wikipedia.org/wiki/...gian_wolf#Basal_wolf

Beringian wolf

The Beringian wolf is an extinct population of wolf (Canis lupus) that lived during the Ice Age. It inhabited what is now modern-day Alaska, Yukon, and northern British Columbia. Some of these wolves survived well into the Holocene. The Beringian wolf is an ecomorph of the gray wolf and has been comprehensively studied using a range of scientific techniques, yielding new information on their prey species and feeding behaviors. It has been determined that these wolves are morphologically distinct from modern North American wolves and genetically basal to most modern and extinct wolves. The Beringian wolf has not been assigned a subspecies classification and its relationship with the extinct European cave wolf (Canis lupus spelaeus) is not clear.

===========================================================

https://en.wikipedia.org/wiki/Cave_wolf

Cave Wolf


*************
“Those who control the present, control the past and those who control the past control the future.” George Orwell, 1984
https://www.google.com/search?...sclient=gws-wiz-serp

Degenerate 1:1
1 Then Trump said, "Let Us re-make a Nation in MY Image, after My likeness, to rule over everything in the Nation, and over all the earth itself and every creature that crawls upon it".

Degenerate 1:2
2 Then Trump said, "Vengeance is mine, I will repay on your behalf."

Degenerate 1:3
3 "My Kingdom come, My will be done."

"When fascism comes to America, it will be wrapped in the flag and carrying a cross." - Sinclair Lewis

O.J. Trump aka Trumpism's Founding Farter, aka Farter Martyr.

"Be careful. When a democracy is sick, fascism comes to its bedside, but it is not to inquire about its health." - Albert Camus


 
Posts: 24527 | Location: Rural | Registered: 17 February 2017Reply With Quote
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Start a pack in Rock Springs Park. Keep the squirrels in line...


TomP

Our country, right or wrong. When right, to be kept right, when wrong to be put right.

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Posts: 15506 | Location: Moreno Valley CA USA | Registered: 20 November 2000Reply With Quote
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Don't get me started. Squirrels are interesting too, literally and metaphorically. Wink Smiler


*************
“Those who control the present, control the past and those who control the past control the future.” George Orwell, 1984
https://www.google.com/search?...sclient=gws-wiz-serp

Degenerate 1:1
1 Then Trump said, "Let Us re-make a Nation in MY Image, after My likeness, to rule over everything in the Nation, and over all the earth itself and every creature that crawls upon it".

Degenerate 1:2
2 Then Trump said, "Vengeance is mine, I will repay on your behalf."

Degenerate 1:3
3 "My Kingdom come, My will be done."

"When fascism comes to America, it will be wrapped in the flag and carrying a cross." - Sinclair Lewis

O.J. Trump aka Trumpism's Founding Farter, aka Farter Martyr.

"Be careful. When a democracy is sick, fascism comes to its bedside, but it is not to inquire about its health." - Albert Camus


 
Posts: 24527 | Location: Rural | Registered: 17 February 2017Reply With Quote
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Are they really dire wolves?


~Ann


 
Posts: 20257 | Location: The LOST Nation | Registered: 27 March 2001Reply With Quote
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Neat and of course a Pandora’s box.

How bout bringing back Dire Straits? Sultans of Swing
 
Posts: 3806 | Registered: 27 November 2014Reply With Quote
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quote:
Originally posted by Aspen Hill Adventures:
Are they really dire wolves?


Everything have chick is not scholarly says they are genetic dire. However, those are reporting what the team says they did.

Checks for free, TommyHawk
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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I’m all for returning the dire wolf if reasonable…

But these are not dire wolves; they may be close and the science involved is something we should be working on.

As to the rationale I would have to reintroducing an extinct species-

Why did they go extinct, and has the reason for that extinction gone away?

Can we accurately do it?

Does returning the species actually fill an ecological niche that is missing?

So if dire wolves were made extinct by humans, reintroduction in an area where they are gone might be rational. But if the reason the dire wolves died out was their large size was beneficial to survival in a ice age and their niche was predating on the megafauna on North America (mastodon, wooly rhino, giant ground sloth, etc.) there isn’t a niche for them and the dislocations caused by reintroducing them and protecting them will be as bad or worse than their extinction.

Compare the dire wolf to the tasmainian tiger… that was killed off by humans introduced mammals- that were more efficient in that niche. That and the prey species were outcompeted by old world species like rats and rabbits. Reintroduce the species and it’s going to die out again absent some significant human acts that will have other downstream effects.

I don’t know if reintroducing the mammoth (as cool as that would be) is feasible given the current state of the tundra and taiga.
 
Posts: 12000 | Location: Minnesota USA | Registered: 15 June 2007Reply With Quote
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Keep in mind there’s been no suggestion of releasing any of these genetic experiments into the broader environment. These are ‘lab rats’ to see what’s possible.

You have to start someplace if you want to figure out how to clone mindless super soldiers in your quest to take over the world. Wink
 
Posts: 6602 | Location: Alberta | Registered: 14 November 2002Reply With Quote
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quote:
Originally posted by crbutler:
I’m all for returning the dire wolf if reasonable…

But these are not dire wolves; they may be close and the science involved is something we should be working on.

As to the rationale I would have to reintroducing an extinct species-

Why did they go extinct, and has the reason for that extinction gone away?

Can we accurately do it?

Does returning the species actually fill an ecological niche that is missing?

So if dire wolves were made extinct by humans, reintroduction in an area where they are gone might be rational. But if the reason the dire wolves died out was their large size was beneficial to survival in a ice age and their niche was predating on the megafauna on North America (mastodon, wooly rhino, giant ground sloth, etc.) there isn’t a niche for them and the dislocations caused by reintroducing them and protecting them will be as bad or worse than their extinction.

Compare the dire wolf to the tasmainian tiger… that was killed off by humans introduced mammals- that were more efficient in that niche. That and the prey species were outcompeted by old world species like rats and rabbits. Reintroduce the species and it’s going to die out again absent some significant human acts that will have other downstream effects.

I don’t know if reintroducing the mammoth (as cool as that would be) is feasible given the current state of the tundra and taiga.


Dire Wolves like the mammoth had their shot. They could not cut it in their niche in their time. None of this should be happening.
 
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According to the company, they expect to have wooly mammoths produced by 2028…


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Posts: 14062 | Location: Georgia | Registered: 28 October 2006Reply With Quote
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Really?

Why did they not cut it?

If you believe the greenies, it’s all a man made issue.

While not common, I’ve seen one wolf that I thought might go 150#. If so, the biggest “difference”- size- is not absolute.

Yes, these 3 hybrids are a science experiment… but if they don’t let them breed (they claim they will not) then it’s not even really an accurate report.

quote:
Originally posted by LHeym500:
quote:
Originally posted by crbutler:
I’m all for returning the dire wolf if reasonable…

But these are not dire wolves; they may be close and the science involved is something we should be working on.

As to the rationale I would have to reintroducing an extinct species-

Why did they go extinct, and has the reason for that extinction gone away?

Can we accurately do it?

Does returning the species actually fill an ecological niche that is missing?

So if dire wolves were made extinct by humans, reintroduction in an area where they are gone might be rational. But if the reason the dire wolves died out was their large size was beneficial to survival in a ice age and their niche was predating on the megafauna on North America (mastodon, wooly rhino, giant ground sloth, etc.) there isn’t a niche for them and the dislocations caused by reintroducing them and protecting them will be as bad or worse than their extinction.

Compare the dire wolf to the tasmainian tiger… that was killed off by humans introduced mammals- that were more efficient in that niche. That and the prey species were outcompeted by old world species like rats and rabbits. Reintroduce the species and it’s going to die out again absent some significant human acts that will have other downstream effects.

I don’t know if reintroducing the mammoth (as cool as that would be) is feasible given the current state of the tundra and taiga.


Dire Wolves like the mammoth had their shot. They could not cut it in their niche in their time. None of this should be happening.
 
Posts: 12000 | Location: Minnesota USA | Registered: 15 June 2007Reply With Quote
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Very short sighted.

All the African endangered species should be introduced to Australia just to get the part started. Wolly mammoth and sabertooth tigers should be introduced in Alaska and the prehistoric bison should be introduced to Canada
.
I'll settle for a hybrid species of pheasant that can survive in Alaska. Something bigger, maybe snowgoose size.
 
Posts: 10198 | Location: Dillingham Alaska | Registered: 10 April 2006Reply With Quote
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quote:
the prehistoric bison should be introduced to Canada


We already have them, our Senate is full of them. I’d cheerfully put a couple of your sabre toothed tigers in there with them and just lock the doors for a couple of weeks.
I don’t think we have any tariff on tigers yet.
 
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quote:
Originally posted by crbutler:
Really?

Why did they not cut it?

If you believe the greenies, it’s all a man made issue.

While not common, I’ve seen one wolf that I thought might go 150#. If so, the biggest “difference”- size- is not absolute.

Yes, these 3 hybrids are a science experiment… but if they don’t let them breed (they claim they will not) then it’s not even really an accurate report.

quote:
Originally posted by LHeym500:
quote:
Originally posted by crbutler:
I’m all for returning the dire wolf if reasonable…

But these are not dire wolves; they may be close and the science involved is something we should be working on.

As to the rationale I would have to reintroducing an extinct species-

Why did they go extinct, and has the reason for that extinction gone away?

Can we accurately do it?

Does returning the species actually fill an ecological niche that is missing?

So if dire wolves were made extinct by humans, reintroduction in an area where they are gone might be rational. But if the reason the dire wolves died out was their large size was beneficial to survival in a ice age and their niche was predating on the megafauna on North America (mastodon, wooly rhino, giant ground sloth, etc.) there isn’t a niche for them and the dislocations caused by reintroducing them and protecting them will be as bad or worse than their extinction.

Compare the dire wolf to the tasmainian tiger… that was killed off by humans introduced mammals- that were more efficient in that niche. That and the prey species were outcompeted by old world species like rats and rabbits. Reintroduce the species and it’s going to die out again absent some significant human acts that will have other downstream effects.

I don’t know if reintroducing the mammoth (as cool as that would be) is feasible given the current state of the tundra and taiga.


Dire Wolves like the mammoth had their shot. They could not cut it in their niche in their time. None of this should be happening.


Really, man was no different from any other creature in competition. Wolves made it. Dire did not. It was not deforestation or the building of a hydro electric dams. They had their chance and could not adapt to changes in both environment and creature conflict. Some did. They are not extinct because humans introduced a species into their environment. Humans did not artificially end the Dire. The Wooly is not adapted to modern climate.

Agains, wolves evolved along side Dire. Wolves won.
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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When can we hunt these wolves with spears and atlatls?
Is a deadfall considered hunting for Mammoths?
Maybe just breed the mammoths for meat, hides and ivory.


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Posts: 27726 | Location: Where tech companies are trying to control you and brainwash you. | Registered: 29 April 2005Reply With Quote
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What I want are pterodactyls!!!! I want to ride one like a dragon! Pterodactyls are scary as fuck. Like flying sharks!


577 BME 3"500 KILL ALL 358 GREMLIN 404-375

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Posts: 27726 | Location: Where tech companies are trying to control you and brainwash you. | Registered: 29 April 2005Reply With Quote
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Supposedly the prehistoric peoples used mass hunting techniques on some of the various megafauna and the debate is that by disrupting the bigger prey species the dire was unable to compete with wolves when dealing with smaller prey animals. Another theory is that as the glaciers and cold receded bigger animals are more efficient in cold and they lost out to smaller wolves.

Note that the extinct prairie wolf and some of the others that the greenies are restocking are actually larger timber wolves from the north… not an accurate repopulation attempt, but moving a different species in to a presumptive empty niche.

Wildlife management was one of my undergrad degrees… there was a lot of debate back then that what we are doing now is not a good idea, for that reason.

quote:
Originally posted by LHeym500:
quote:
Originally posted by crbutler:
Really?

Why did they not cut it?

If you believe the greenies, it’s all a man made issue.

While not common, I’ve seen one wolf that I thought might go 150#. If so, the biggest “difference”- size- is not absolute.

Yes, these 3 hybrids are a science experiment… but if they don’t let them breed (they claim they will not) then it’s not even really an accurate report.

quote:
Originally posted by LHeym500:
quote:
Originally posted by crbutler:
I’m all for returning the dire wolf if reasonable…

But these are not dire wolves; they may be close and the science involved is something we should be working on.

As to the rationale I would have to reintroducing an extinct species-

Why did they go extinct, and has the reason for that extinction gone away?

Can we accurately do it?

Does returning the species actually fill an ecological niche that is missing?

So if dire wolves were made extinct by humans, reintroduction in an area where they are gone might be rational. But if the reason the dire wolves died out was their large size was beneficial to survival in a ice age and their niche was predating on the megafauna on North America (mastodon, wooly rhino, giant ground sloth, etc.) there isn’t a niche for them and the dislocations caused by reintroducing them and protecting them will be as bad or worse than their extinction.

Compare the dire wolf to the tasmainian tiger… that was killed off by humans introduced mammals- that were more efficient in that niche. That and the prey species were outcompeted by old world species like rats and rabbits. Reintroduce the species and it’s going to die out again absent some significant human acts that will have other downstream effects.

I don’t know if reintroducing the mammoth (as cool as that would be) is feasible given the current state of the tundra and taiga.


Dire Wolves like the mammoth had their shot. They could not cut it in their niche in their time. None of this should be happening.


Really, man was no different from any other creature in competition. Wolves made it. Dire did not. It was not deforestation or the building of a hydro electric dams. They had their chance and could not adapt to changes in both environment and creature conflict. Some did. They are not extinct because humans introduced a species into their environment. Humans did not artificially end the Dire. The Wooly is not adapted to modern climate.

Agains, wolves evolved along side Dire. Wolves won.
 
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Again, Dire Wolves could not compete. Wolves did.
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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The movement to introduce these extinct species is called rewilding.

I once wrote a science fiction novelette (published here: https://www.amazon.com/Years-B...%2Caps%2C311&sr=8-15 ) about an effort to reintroduce the extinct giant beaver.
 
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quote:
Originally posted by RolandtheHeadless:
The movement to introduce these extinct species is called rewinding.

I once wrote a science fiction novelette (published here: https://www.amazon.com/Years-B...%2Caps%2C311&sr=8-15 ) about an effort to reintroduce the extinct giant beaver.


You mean like Lizzo?? animal


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Posts: 14062 | Location: Georgia | Registered: 28 October 2006Reply With Quote
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Sorry, I don't follow you there. Who is Lizzo?
 
Posts: 7816 | Location: Coeur d' Alene, Idaho, USA | Registered: 08 March 2013Reply With Quote
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they re-introduced bisons, moose, wolf, sheep and many other species even with success so why not
 
Posts: 3490 | Location: Whitehorse, Yukon, Canada. | Registered: 21 May 2006Reply With Quote
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A previously extinct species will be a re-introduced species. It has no normal prey and doesn't belong there, so it is an invasive animal.

Interesting science, but what do you do with them?
 
Posts: 11037 | Location: Houston, Texas | Registered: 26 December 2005Reply With Quote
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quote:
Originally posted by medved:
they re-introduced bisons, moose, wolf, sheep and many other species even with success so why not


Those species are not extinct and were the result of modern sport hunting. I will add the idea of repating non extinct animals to traditional ranges in high concentrations, but limited range is dubious so a sound management plan. That applies to herbivores.


The Dire Wolf was not made extinct through building a hydro electric dam or unregulated market hunting w the species surviving. They had their shot and failed. I would not permit the use of dna sequencing in this manner. Likewise, no one is arguing the habit exists to support Wooly Mammoths. Thus, no.

Dire Wolfs probably could not breed with canids according to the conclusions of a 2021 scientific paper. Wolves arrived from Asia. Colossal claims the Dire Wolf and wolves share 99.5 percent of the same DNA. However, assuming that is true, Colossal has not released the entire genome they say they have completely sequenced. Assuming the 99.5 percent number is accurate, the grey wolf genome is 2.4 billion base pairs. That leaves room for millions of base pairs to be different. Thus, these creatures are truly Jurassic Park mutants. Sorry, I do not appreciate this use of science.


Similar morphologically to the extant grey wolf, dire wolves were a highly divergent lineage that split from living canids around 5.7 million years ago. In contrast to numerous examples of hybridization across Canidae2,3, there is no evidence for gene flow between dire wolves and either North American grey wolves or coyotes. This suggests that dire wolves evolved in isolation from the Pleistocene ancestors of these species. Our results also support an early New World origin of dire wolves, while the ancestors of grey wolves, coyotes and dholes evolved in Eurasia and colonized North America only relatively recently.

Fire Wolves did not become extent due to “non-natural” endeavors of humans. Fire Wolves lost to wolves. There is no place for them. They and their kind should remain as concluded. They should not be hybridized back into a life of captivity. Such hybrids could not be self sustaining and would be genetic science fair projects artificially placed to combat with species that long out competed them. Let’s assume this hybrid, mutants could now breed w grey wolves. It would be poker conservation and science to place a new mega predator into a limited environment to breed and compete w the species that is supposed to by evolution/adaption here.

Further reading tells me that 5 of the genetic changes in grey wolves genetics that were selected to give them grey wolf white coats. Stayed better, those five edits were grey wolf genes to make the grey wolf gene for white coats express. Thus, only 15 edits were The Dire Wolf DNA. Again, it appears Colossal position is that the dna vastly overlaps. Thus, these edits have returned the species by morphology according to Colossal.

Beth Shapiro who is the science head to all this has stated, “Species concept are human classifications, and everybody can disagree, and everyone can be right…You can use the phylogenetic species concept to determine what you are going to call a species, which is what you are implying…we are using the morphological spices concept, and saying if they look like this animal, then they are this animal.”

Thus, Jurassic Park science fair hybrids.

Now, I’ll be up front. I am old fashion and use the old when two can breed and produce viable offspring, then they are the same species. I am not hard in the fans splitters camp. However, I bet these pups can breed with grey wolfs producing viable off spring. Where as, Dire Wolfs could not.


No doubt these are morphologically Dire wolf by appearance. However, an advisor employed by Colossal, a Professor Love Dylan, has stated these are 99.9 percent Grey Wolves. Colossal surges at this taking the position both have 99.5 percent dna overlay. Again, Dire Woves diverged from wolves and are not dire wolves were a highly divergent lineage that split from living canids around 5.7 million years ago. In contrast to numerous examples of hybridization across Canidae2,3, there is no evidence for gene flow between dire wolves and either North American grey wolves or coyotes. This suggests that dire wolves evolved in isolation from the Pleistocene ancestors of these species. Dire Wolves then lost the battle to wolves when they crossed from Asia. This is not returning grey wolves to a range they were market hunted from.

I said these things when they crossed a lion with a tiger to create a non-viable science fair mutant.
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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Dire Wolves were not created here. MSN did something nature could not do. Man hybridized Dire Wolves and wolves. We created a new species. A new major predator.

That is not good science. That is dangerous. This needs strong regulation.
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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They are just wolves with CRISPR mods to make them look like dire wolves.
No ancient DNA used. No ability to presume they would behave like a dire wolf In individual or social behaviour.
Can't do anything with them, and there are some serious concerns from knowledgable people about the use of CRISPR and its ability to jump host or spread in a host population.
Im unsure of what the end goal is with this, other than publicity.
 
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Gonna bet someone here would shoot the first Irish elk they "make."


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quote:
Originally posted by RolandtheHeadless:
Sorry, I don't follow you there. Who is Lizzo?

A photo of a giant beaver………AKA Lizzo

https://images.app.goo.gl/L6ZYHtoDn6oW8X6q6


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Posts: 14062 | Location: Georgia | Registered: 28 October 2006Reply With Quote
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Is there a way to DECL0NE living creatures?

Start with politicians, lawyers, bankers, influencers, activists etc?? rotflmo


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Posts: 72202 | Location: Dubai, UAE | Registered: 08 January 1998Reply With Quote
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No one is talking about reintroducing dire wolves to the wild.

While I don’t disagree that releasing this sort of hybrid needs very careful thought, and I agree this is not a dire wolf due to the methodology more than interbreeding (taking a wolf genome and making selective edits is certainly more properly a hybrid than a clone) it is a step and is a more popular choice of animal than, say, a prairie wolf or an aurochs.

I look at the quagga project as similar. They are trying to backbreed a quagga from a zebra- it’s a zebra hybrid that looks like a quagga.

If we can clone up a prairie wolf, I’d support reintroduction of those in Colorado… not the northern timber wolves they are doing now.

The argument is whether biodiversity is good or not.

Science is not particularly strong on why the dire wolf died out.

Was it the present wolf came across from Asia and we have a variant of naturally occurring invasive species?

I certainly have issues with releasing these into the wild. We don’t know what would happen, but Hyem’s argument that they were outcompeted then actually is a reason it is not a concern- release a bunch of dire wolves and in 20-60 years (assuming they cannot interbreed, which strikes me as a major assumption) they will die out again and unless we actively intervene…

The whole Jurassic park theme of reintroduction of extinct species and they could be more competitive than the current animals kind of implies evolution is not as described.

Frankly, I reject the idea that sport hunting has caused extinction. It can be a pressure, but the big one is loss of habitat and changes in the biome.

The closest item would be the bison, and even there it was probably more introduced disease than the hunting that did them badly.

Wolves? Again, not hunting but organized agriculture and trapping for eradication killed species like the prairie wolf, not “sport hunting”.
 
Posts: 12000 | Location: Minnesota USA | Registered: 15 June 2007Reply With Quote
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Their ecosystem no longer exists. Thus, their is no reason to engage in this bastardized science.

No one has argued sport hunting. We have argued market hunting has had a strong impact. I include the trapping on market hunting due to bounties.

There are a lot of things running around that were not intended to be released.

The North American Model of conservation.
 
Posts: 14753 | Location: Somewhere above Tennessee and below Kentucky  | Registered: 31 July 2016Reply With Quote
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https://wapo.st/3R88Yvc

Trump team cites wolf ‘de-extinction’ as it seeks to cut endangered species list
The interior secretary hailed a biotech company’s claim to have brought back the dire wolf, while the administration and GOP push to roll back species protections.

Updated today at 1:54 p.m. EDT


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Posts: 24527 | Location: Rural | Registered: 17 February 2017Reply With Quote
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quote:
Originally posted by LHeym500:
quote:
Originally posted by medved:
they re-introduced bisons, moose, wolf, sheep and many other species even with success so why not


Those species are not extinct and were the result of modern sport hunting. I will add the idea of repating non extinct animals to traditional ranges in high concentrations, but limited range is dubious so a sound management plan. That applies to herbivores.


The Dire Wolf was not made extinct through building a hydro electric dam or unregulated market hunting w the species surviving. They had their shot and failed. I would not permit the use of dna sequencing in this manner. Likewise, no one is arguing the habit exists to support Wooly Mammoths. Thus, no.

Dire Wolfs probably could not breed with canids according to the conclusions of a 2021 scientific paper. Wolves arrived from Asia. Colossal claims the Dire Wolf and wolves share 99.5 percent of the same DNA. However, assuming that is true, Colossal has not released the entire genome they say they have completely sequenced. Assuming the 99.5 percent number is accurate, the grey wolf genome is 2.4 billion base pairs. That leaves room for millions of base pairs to be different. Thus, these creatures are truly Jurassic Park mutants. Sorry, I do not appreciate this use of science.


Similar morphologically to the extant grey wolf, dire wolves were a highly divergent lineage that split from living canids around 5.7 million years ago. In contrast to numerous examples of hybridization across Canidae2,3, there is no evidence for gene flow between dire wolves and either North American grey wolves or coyotes. This suggests that dire wolves evolved in isolation from the Pleistocene ancestors of these species. Our results also support an early New World origin of dire wolves, while the ancestors of grey wolves, coyotes and dholes evolved in Eurasia and colonized North America only relatively recently.

Fire Wolves did not become extent due to “non-natural” endeavors of humans. Fire Wolves lost to wolves. There is no place for them. They and their kind should remain as concluded. They should not be hybridized back into a life of captivity. Such hybrids could not be self sustaining and would be genetic science fair projects artificially placed to combat with species that long out competed them. Let’s assume this hybrid, mutants could now breed w grey wolves. It would be poker conservation and science to place a new mega predator into a limited environment to breed and compete w the species that is supposed to by evolution/adaption here.

Further reading tells me that 5 of the genetic changes in grey wolves genetics that were selected to give them grey wolf white coats. Stayed better, those five edits were grey wolf genes to make the grey wolf gene for white coats express. Thus, only 15 edits were The Dire Wolf DNA. Again, it appears Colossal position is that the dna vastly overlaps. Thus, these edits have returned the species by morphology according to Colossal.

Beth Shapiro who is the science head to all this has stated, “Species concept are human classifications, and everybody can disagree, and everyone can be right…You can use the phylogenetic species concept to determine what you are going to call a species, which is what you are implying…we are using the morphological spices concept, and saying if they look like this animal, then they are this animal.”

Thus, Jurassic Park science fair hybrids.

Now, I’ll be up front. I am old fashion and use the old when two can breed and produce viable offspring, then they are the same species. I am not hard in the fans splitters camp. However, I bet these pups can breed with grey wolfs producing viable off spring. Where as, Dire Wolfs could not.


No doubt these are morphologically Dire wolf by appearance. However, an advisor employed by Colossal, a Professor Love Dylan, has stated these are 99.9 percent Grey Wolves. Colossal surges at this taking the position both have 99.5 percent dna overlay. Again, Dire Woves diverged from wolves and are not dire wolves were a highly divergent lineage that split from living canids around 5.7 million years ago. In contrast to numerous examples of hybridization across Canidae2,3, there is no evidence for gene flow between dire wolves and either North American grey wolves or coyotes. This suggests that dire wolves evolved in isolation from the Pleistocene ancestors of these species. Dire Wolves then lost the battle to wolves when they crossed from Asia. This is not returning grey wolves to a range they were market hunted from.

I said these things when they crossed a lion with a tiger to create a non-viable science fair mutant.


did you look how they created those wolf ...

the animals i cited were not all vanished because of human hunting but you are right they were not created in manipulating DNA ...

im all for species reintroduced back even if they vanished ...
 
Posts: 3490 | Location: Whitehorse, Yukon, Canada. | Registered: 21 May 2006Reply With Quote
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Heym, you said we were not arguing sport hunting, yet here you state that the (localized) extinctions were the result of sport hunting.

quote:
Originally posted by LHeym500:
quote:
Originally posted by medved:
they re-introduced bisons, moose, wolf, sheep and many other species even with success so why not


Those species are not extinct and were the result of modern sport hunting. I will add the idea of repating non extinct animals to traditional ranges in high concentrations, but limited range is dubious so a sound management plan. That applies to herbivores.


The Dire Wolf was not made extinct through building a hydro electric dam or unregulated market hunting w the species surviving. They had their shot and failed. I would not permit the use of dna sequencing in this manner. Likewise, no one is arguing the habit exists to support Wooly Mammoths. Thus, no.

Dire Wolfs probably could not breed with canids according to the conclusions of a 2021 scientific paper. Wolves arrived from Asia. Colossal claims the Dire Wolf and wolves share 99.5 percent of the same DNA. However, assuming that is true, Colossal has not released the entire genome they say they have completely sequenced. Assuming the 99.5 percent number is accurate, the grey wolf genome is 2.4 billion base pairs. That leaves room for millions of base pairs to be different. Thus, these creatures are truly Jurassic Park mutants. Sorry, I do not appreciate this use of science.


Similar morphologically to the extant grey wolf, dire wolves were a highly divergent lineage that split from living canids around 5.7 million years ago. In contrast to numerous examples of hybridization across Canidae2,3, there is no evidence for gene flow between dire wolves and either North American grey wolves or coyotes. This suggests that dire wolves evolved in isolation from the Pleistocene ancestors of these species. Our results also support an early New World origin of dire wolves, while the ancestors of grey wolves, coyotes and dholes evolved in Eurasia and colonized North America only relatively recently.

Fire Wolves did not become extent due to “non-natural” endeavors of humans. Fire Wolves lost to wolves. There is no place for them. They and their kind should remain as concluded. They should not be hybridized back into a life of captivity. Such hybrids could not be self sustaining and would be genetic science fair projects artificially placed to combat with species that long out competed them. Let’s assume this hybrid, mutants could now breed w grey wolves. It would be poker conservation and science to place a new mega predator into a limited environment to breed and compete w the species that is supposed to by evolution/adaption here.

Further reading tells me that 5 of the genetic changes in grey wolves genetics that were selected to give them grey wolf white coats. Stayed better, those five edits were grey wolf genes to make the grey wolf gene for white coats express. Thus, only 15 edits were The Dire Wolf DNA. Again, it appears Colossal position is that the dna vastly overlaps. Thus, these edits have returned the species by morphology according to Colossal.

Beth Shapiro who is the science head to all this has stated, “Species concept are human classifications, and everybody can disagree, and everyone can be right…You can use the phylogenetic species concept to determine what you are going to call a species, which is what you are implying…we are using the morphological spices concept, and saying if they look like this animal, then they are this animal.”

Thus, Jurassic Park science fair hybrids.

Now, I’ll be up front. I am old fashion and use the old when two can breed and produce viable offspring, then they are the same species. I am not hard in the fans splitters camp. However, I bet these pups can breed with grey wolfs producing viable off spring. Where as, Dire Wolfs could not.


No doubt these are morphologically Dire wolf by appearance. However, an advisor employed by Colossal, a Professor Love Dylan, has stated these are 99.9 percent Grey Wolves. Colossal surges at this taking the position both have 99.5 percent dna overlay. Again, Dire Woves diverged from wolves and are not dire wolves were a highly divergent lineage that split from living canids around 5.7 million years ago. In contrast to numerous examples of hybridization across Canidae2,3, there is no evidence for gene flow between dire wolves and either North American grey wolves or coyotes. This suggests that dire wolves evolved in isolation from the Pleistocene ancestors of these species. Dire Wolves then lost the battle to wolves when they crossed from Asia. This is not returning grey wolves to a range they were market hunted from.

I said these things when they crossed a lion with a tiger to create a non-viable science fair mutant.
 
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