I'm pretty big on penetration and edible meat. I've been a big fan of Barnes monometal bullets since the first X bullets. . Since I've killed lots of deer with carts that typically are used for elephant having an exit hole is mandatory. For the poster that gets the great accuracy with the 130 Sirocco's, you should run your own drops to insure the bc is on. Brian Lintz claims that bullets bc is in the high. 4 s. That bullet is one of my goto bullets in my 6.5 Creedmoor but really I would prefer it was a 140 gr with a true bc of. 6 or better. . My rifle likes the 140 gr Hornady SST and tho its not a tough bullet it should work good on caribou, deer and wolves. . Barnes and GS Custom should make a. 6+ bc expanding bullet or at least,. 550 bc! In the 6.5 . Those hunters that like bomb bullets can keep using them but real world big game hunting means shots can be real close sometimes .
Would I shoot a game animal with a target bullet , sure. Have several times. But if its a tricky shot on an animal that's walking away I would have to pass it up. Not something I want to do.

I have long range guns but have only made one shot at 500yds. I use hunting bullets, mostly TSX in my .300's.
I have some RWS factory ammo that is amazingly accurate as well.
Sometimes I think we get a bit caught up in the bullet types as most of today's bullets are very good for target and hunting.