A fairly new one:

"I guess it never occured to you that you might actually have to bleed to pull off this little coup"

--Lucien in Underworld

"Use enough dynamite there, Butch?"

(Butch Cassidy and the Sundance Kid)

"Wakie Wakie, Eggs and Bakie"

(sp?) (Kill Bill II)

Here is Johny ;-) . . . Shining

...I can walk on water, eat bullets and shit ice cream...

Can't remember who that was.

From the first Ace Ventura movie when Sean Young, playing a police detective, asks Ace if he'd like her to make his life a living hell: "Why, thanks for the offer, Lois, but I'm really not ready for a relationship right now." Kills me every time I see it...

A man has got to know his limitations-Clint,,,,,,,Clay

The last scene when James Cagney was going to the chair in "Angels with Dirty Faces"

Top of the world Ma in "White Heat" with James Cagney

Just put your lips together and blow, Lauren Bacall with Humphrey Bogart and the title escapes me momentarily.

Tommy Lee Jones in Under Siege:
"I'm tired of coming up with last minute solutions to impossible problems brought on by other fucking people."

John Wayne in True Grit, when Kim Darby swims her horse across the river after them:
"By God, she reminds me of me!"

Bill Murray in Stripes:
"We're Americans, with a capital A. Do you know what that means? Do ya? That means our forefathers were kicked out of every decent country in the world!"

Jim

Major Ashley-Pitt: In our experience, Americans are uncouth misfits who should be run out of their own barbaric country.

Matthew Quigley: Well, Lieutenant...

Major Ashley-Pitt: Major.

Matthew Quigley: Major. We already run the misfits outta our country. We sent 'em back to England.

(from Quigley Down Under)