Both are awsome rounds. Squirrel will take more dies and forming steps. Squirrel is alot more mild. Either should perform well from that set up. Squirrel is about the equal to a 22mag. More blast and recoil with the bee. I would lean towards the Bee, more horse power, a little more accurate. Reduce the loads and equal a squirrel to kill paper. Less money in dies, less steps. My choice 20 Ack Bee or HeeBee. I am trying to make up my mind on a 20 right now. Rifle platform and 222 case. There are a ton. I think VV chambers both. They might help. Woodchuck den is always a good place for info.