I have booked a beutiful Sauer take down with two barrels: 8x 68 and 416 rem mag.
Someone said me this gun usually loose his accuracy after few shots and I'm very worry about this.
Someone have experience about this rifle and can say something about this accuracy for long time?

I don't trust any takedown system; I believe that a "regular" action is much stronger and steadier. An acquaintance, some years ago, bought a Mauser 66 takedown, cal. 270W; I suppose that it was a craftman alteration; despite the apparent solidity and the tight fitting of the takedown system and many different reloads and manufactured cartridges tested, we couldn't get any decent group from this rifle; the guy sold it after few months.