Here is a nice moderate speed load that I shoot in a Mauser in .500 Jeffery:
Primer: Federal 215 Match
Brass: Horneber
Powder: IMR-3031; 104 grains
Bullet: 535 grain Woodleigh, softs and solids
High-2339; Low-2323; Mean-2329; SD-6 (solids)
Crimped with Lee factory crimping die; bullets seated in cannelure.