I have used the 225 grain Hornady on a few Kudu's and they performed verry well, did not recover any bullets, the were going about 2800 fps, but I used local powder. If you can get the 225 grain in neat groops you will have a very good combination, mine shoots 18 mm groups wit the Hornady bullets

I took an Elk last year with the 225 Accubond. I like it's accuracy and ballistic coefficient. Terminal performance was excellent. I intend to use it unless I'm going after something larger than Colorado Elk.
Whatever bullet weight I've tried from 210 to 250 grain I've had uniformly excellent luck with IMR-4350 in the 338 Win Mag. I try it first in any 338 Win Mag I load for (9 or 10 so far)................DJ

I used the 225gr TSX on moose this year and they are wonderful.My load was 72gr RL 19 which gives me less than a 1 inch group. Not sure of the velocity but it should be around 2800 fps. I also used a 250gr Hornady RN on a Black Bear and of course they also work. I have some 250gr Barnes X that I need to work up for Grizzly, but it seems as though few people use this bullet in the .338 WM?? So I am also waiting for some reports on this combo.
Cheers
Allan

Best accuracy and velocity with the following loads with a 24" barrel. I dont use magnum primers.

185 TSX 77 grains of 760 3,160 fps

225 Accubond 73.2 grains of N160 2,880 fps

250 NP 80 grains of RL25 2,800 fps

If you're a serious hunter and this isn't just some grand experiment and you want consistent results you have two choices. 250 grain Swift A-frames or 230 grain FailSafes, anything else is just experimentation.

I've been using the .338 since 1980. Two pre 64 model 70 Alaskan's and one Ruger 77. Current rifle is a 1958 Alaskan with a 25" barrel. I've shot several bull elk each with the Hornaday 225 spire point and the Nosler 250 partition. Both are excellent bullets, but I lean towards the Hornaday. It shoots flatter with less recoil and penetrates just as well. Bullets don't have to be heavy to penetrate well, they just have to be constructed properly and that Hornaday fills the bill. I 've only recovered one Hornaday and that one broke 4 ribs on a running spike bull, hard quartering away (you could put your hand inside the entry hole it made) the bullet went up through the chest and I found it against the skin in the front of his neck! My partner used a .375 for years on elk in Oregon and he was very impressed with that bullets performance. They are also inexpensive and can be found anywhere bullets are sold. IMR 4895 and 4350 work well. BT53

I have been using the .338 since its birth..I have hunted all over the world with it..Shot everything form Rockchucks, Duiker and Jackrabbits to a few Cape Buffalo and joined in on a Lion kill with it...

I settled on three bullets...the 210 Nosler at 3005 FPS for most stuff, the 300 gr. Woodleigh at 2400 FPS in soft and solid for anything..with a 250 gr. Nosler tossed in now and then for an elk hunt.....Since they all shoot to the same POI in my gun, I see no reason to change anything.

I totally agree with Ray on the 210 Nosler Partition. It's pretty much all you'll ever need in the US. My 26" barrel A-Bolt shoots them into .75 MOA at 3050 fps. The results on elk have been nothing short of remarkable. It puts them down right now !!! I use IMR 4350 in my load and Federal 215 primers.

We have had great luck with the 225 Northfork Soft in three guns this season.

Powder of choice Norma MRP / Re 22. You can reach almost 2900f/s in the long tubes making it shoot plenty flat.

Reliable expansion and great penetration. Have no recovered bullets so far. Game ranging from Roe deer to Moose