Paul B,

Thanks for the info, it seems strange to use Imr 4350 in this case. Yes, I will work up slowly as my 35 Whelen is built on a 1903 Springfield action. No need to push it.

BigBullet

Big Bullet. The 275 gr. Hornadys were discontinued in 1967. The only data I know of is in the Hornady loading manual #1 Circa 1967.
Data is as follows.
All powders designated as IMR are the version made by Du Pont. Current IMR powders made by IMR are somewhat faster burning. Starting loads should be OK, but be real careful with the max loads.
IMR-3031 start 41.0 gr. 1900 FPS Max 48.8 gr. 2300 FPS
IMR-4064 44.0 gr. 1900 FPS 51.5 gr. 2300 FPS
IMR-4895 43.8 gr. 1900 FPS 52.0 gr. 2300 FPS
IMR-4320 44.4 gr. 1900 FPS 52.6 gr. 2300 FPS
BL-C2 48.4 gr. 2100 FPS 53.1 gr. 2300 FPS
H-380 46.9 gr. 2000 FPS 55.1 gr. 2300 FPS
IMR-4350 51.4 gr. 2000 FPS 56.6 gr. 2200 FPS

From the NRA Handloader's guide, again with Du Pont versions of the IMR powders, they show what they consider the max loads for the 300 gr. barnes bullets. Start at least 10, and preferably 15 percent below these charges again due to the faster burning rate of the IMR brand powders.

IMR-3031 Maximum 42.0 gr. 2061 FPS
IMR-4064 48.0 gr. 2190 FPS
IMR-4350 60.0 gr. 2351 FPS Compressed load.

I'm not too comfortable with that last 4350 load, but it may be OK.
At least those should give you some kind of starting point.
Paul B.

""Does anyone have a favorite load for these heavy weights?""

Yes, but we'll have to use my rifle so please send me the bullets roger