SalG, I've never been real high w/ the idea of installing rifle scopes on handguns.
One would have to be VERY careful to avoid getting hit by the ocular bell of the rifle scope. There may be certain situations where it would work, but those are few. Having said that, I've going to experiment
shooting my 22 Rem BR w/ a rifle scope. I use this rig only at the range and on praire dogs. It would have to be a VERY light recoiling round for me to consider a rifle on a gun used in the field. Even then, I'd think issues such as scope/shooter alignment would be challenging.
As to the second part of your question, I have some experience scoping a Striker. I had a difficult time getting a mount/rings combo for my 308 Win Striker that would both fit my scope (Burris 2-7X) and work well.
I tried multiple combinations, including Leupold Quick-detatchable (Weaver style) base/rings (didn't fit as it needed extension rings they don't make for the Weaver style :roll: ) and Weaver extension mounts w/ Weaver rings (scope moved 1/16" every 12 shots
) before I finally sent it to SSK Industries for their T'SOB mount & rings. Then, their rings (med) weren't high enough.
Ended up buying 3 Burris high Z-rings and used w/ the T'SOB base. I've been satisfied w/ this set up. If I had it to do over again, I'd probably first try the Weaver 1 piece base (it has multiple slots in it) and 3 Burris Z-rings. Look at the dimensions of your scope very carefully before ordering your base/rings. Some scopes, especially a short one like the Burris 2-7X, don't allow you much room in which to place rings, especially if you're using more than 2 rings. Longer scopes, such as the Burris 3-9X and 3-12X, are easier to mount. For a 22-250, I'd think 2 rings would be sufficient. After using the Burris Signature rings to mount scopes on the last few Contender barrels, I've decided these are my favorite rings.
Gary T.
Good luck and good hunting.