I'm reading an article in Handloader #275 Dec 2011 by Brian Pearce call Primer Pointers.
In this article he writes about laading 357mag and 44mag. He mentions using H110 powder in freezing temperatures shooting light weight bullets and getting very low velocity from his 44mag.
He recommends using magnum primers with H110 in freezing temps with light loads in the 44mag.

I want to load up some 22 Hornets with Hornady light weight 35 gr Vmax bullets and 12grs of H110 powder. The primer selection for cold weather shoot is the issue. Now my usual summer load uses CCI 500 small pistol primers, I get 3125 fps average.

I want to know if I should move up to a real small rifle magnum primer or go with a Rem 6 1/2 or a standard small rife primer for cold weather shooting. The same magazine (different article) points out that a mag primer can lower extreme velocity spreads when shoot light weight bullets. Maybe a hotter primer would help to reduce extreme velocity spreads I see with the light 35gr bullet I use?

The Hornet been around a long time, someone must have shot one in very cold weather even with factory ammo.

My other load for the 22 Hornet is with Sierra's 45gr "Hornet" bullet and ~13gr of L'll GUN in Winchester cases.
I don't know how L'll GUN behaves in the very cold temperatures either.

Many reloader use mag. primers for the winterhunts. The most important thing is sighting in in the same temp. as you are going to hunt.

i've never had ignition or velocity problem wiht h110 or lil gun in hornets using plain old small rifle primers

I've had no problems using the small pistol primers and 13.0gr of Lilgun in my Hornet, at all. Same load, all year long.