I just wanted to know if I can fire form once fired 22-250 brass that I had from a gun I had a few years ago if I anneal it first? I have a 22-250 ackley coming in a few weeks for my Encore. Any info??? Thanks ahead of time!

The answer is yes. Try not to let the blue color get much below the shoulder. roger

I agree with Roger.

Chuckduster,
Load up a stout load, something you would consider safe in a 22/250. That way you will get cases properly sized to the new chamber and no headspace problems. This is no time for weiner loads.After that you can back off on the charge if you like. You're going to like this chambering, I have two of them and I sure like mine!
Stepchild