I have some 225g Hornady InterLock, has any one load data for these bullets, i see they are not currently available.

Data for the Speer 235 grain bullet is available at Hodgdon and should be safe if you start with the starting loads.

I think the current Hornady Manual for the 225 grn bullet.

The older Hornady manuals have data for the 220 grain bullet used in the .375 Win. Same advice goes start with a starting load and work up.