Does anyone have experience with this combination or one close to it? Thanks for sharing as the $1.40 brass is making experimentation quite expensive.

I've loaded plenty of 200grs Nosler Accubond and 200grs Sierra MK in a custom Rem 700. I use 69grs of Norma 15 (a Borfors powder VERY similar to RL22), WW brass and Federal 215 primers, COL 3.66". Start with 66grs of RL22 and work your way up.
This load shoots small groups and put both bullets in the same place. Speed is about 2900fps (26" Lothar Walther barrel)