I hope that Sierra does not change it's bullet designs as long as I use them I know I can buy a soft fast expanding bullet that is accurate. I know not to slam them into shoulders and like their quick expansion on ribs and lung tissue. The ballistic tips at first were just too quick to expand.

I have very limited hunting experience so my input may be negligable at best.
I have used Sierras for 3 of the four deer I've shot with a rifle.
I use moderate velocity calibers which I think makes a difference when critiquing bullets.
I've shot two does(140 and 160#'s) with Sierras 6.5 160g SPSP out of a 6.5x55 24" tube, both bullets made excellent entry and exit wounds, tore the innards of the animal to pieces and were not recovered.
Both animals ran a very short distance before expiring.
I've also used the Sierra 165g SPBT in 308 out of a 20' barrel with full devastating penetration of a large buck.
I've also used a Nosler 150g BT and had full penetration of the shoulder, heart lungs and off side of a medium sized PA buck.
All my shots have been under 100 yards and closer to 50 yards.
I would use a tougher bullet if I was using my 7mm mag or an '06 based 25,26, or 27 caliber.
But for my 22-2700fps cartridges I don't doubt the Sierras.

One last scientific statement and I am done!

THEY SUCK!

I've read a lot of good and bad about the Gamekings and my only experience with them is that they wouldn't group as well as other bullets in my 308, 300WSM, or 7 mag so I don't use them.