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One of Us |
For what it is worth I visited my doctor (who has hunted Africa three times himself) today and he prescribed Malarone for my wife and me. | |||
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one of us |
Drug-drug interactions are tedious for us MD's. I resort to Epocrates on a Palm Pilot to check for these. Epocrates says: No significant interactions between warfarin and Malarone. It should not affect PT(INR) if you are on the rat poison. Malarone has very few interactions, two listed are rifampin and metoclopramide. Tetracyclines such as doxycycline may counteract the Malarone (affects the Atovaquone component of Malarone), but then the doxy would still be providing some protection from Malaria, and doing a world of good for tick borne disease. Doxy is not a good prophylaxis for traveler's diarrhea. If you have renal insufficiency with creatinine clearance less than 30 ml/min, you should not take Malarone. If you have mild to moderate cirrhosis from all the sundowners, Malarone will probably be O.K., but they don't know for sure about severe cirrhotics, Ruark never took it. Yes, it has only been around for about 10 years. Malarone has easy dosing for kiddies, with pediatric tablets available, and established dosing for those who weigh 11 Kg (22 lbs) or more. Malarone has the least side-effects of all the malaria phrophylactics, greatest safety, and efficacy as good as it gets. I took it in 2001. Best choice for Malaria prophylaxis. | |||
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Thanks RIP. I will go with Malarone again. | |||
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one of us |
Dan, You're spot on. In 1985 I became a chemist but haven't heard of Malarone or Lariam at the faculty of pharmacy. J B de Runz Be careful when blindly following the masses ... generally the "m" is silent | |||
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one of us |
I took my first Lariam in 1987. I still remember one dream in particular. Scary stuff. The drug of choice prior to that was Chlorquine Phosphate. Rich Elliott Rich Elliott Ethiopian Rift Valley Safaris | |||
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one of us |
I hate Larium. I had the same symptoms that Wendell had while on a lioness/bull elephant hunt in the Matetsi in 1994. I wouldn't tell my enemies to use the damn stuff. It just wouldn't be right. | |||
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One of Us |
When I travelled first in Africa in 1988 neither Larium nor Malarone were available. I used the Tropical Diseases Hospital in London. That is only 20 years ago. I travelled again in 1994, 2002 and 2006. And also in several parts of South East Asia. Over a twenty year period it is quite noticeable how medical treatments change for travellors and also what the advice is. ANYONE travelling over an extended period would know this. Of course if malarial preventative medicines might not have changed much since 1999 ...... so some might think it has always been like that. PS I don't take Larium as it does have affects for me. I've used Doxycycline the last few times and the sun sensitivity doesn't bother me. | |||
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