Which would you say would give better penetration.
.375/270gn Failsafe, or .338/275gn A-Frame?

The speed is an important factor here. You did not mention the velocity of each load?
I have tried both bulletweights in the mentioned calibers. If the A-Frame is loaded to high velocity then it will expand a lot which will reduce its penetration (but it will penetrate deeply enough for most purposes no matter what..!). With mediumhigh velocities the 275 grs .338" A-Frame will really penetrate deeply. BUT the Failsafes always penetrates very deep.
I think the two bullet/caliber combinations will be very equal, but maybe my voto for best penetration will go to the .375/ 270 grs FS...

I dont know if one can give a proper answer if you are comparing the two against each other..
I would cut each bullet in half length wise and see what they look like inside and then make your decision on how they work...Also what are you going to use them for??? What animals???

Mike

Both will work just fine any differences are mostly theoretical.

465H&H

Driven at anywhere near the same velocity the Failsafe will always be the better penitrator. the Swift A frame is not a outstanding penitrator, it expands early and large, it is not ment to penitrate like a failsafe or Barnes X or Nosler partition...more like a trophy bonded...

The 270 gr. Fail-Safe is one of the most impressive penetrating bullets I've ever used, and I've shot completely through a grizzly end-to-end with this projectile out of the 375 H&H. This bullet makes most 300 gr. conventional bullets obsolete..........

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