Has anyone ever come across any preference in rate of twist for the 375HH for bullets in the 270 thru 300 grn class?? Is aslower rate better than a faster for the heavier bullets?

General rule of thumb is to use a faster twist rate for heavier bullets.I have not used anything but 270's and 300's in my 375 it shoots both well.
Most of the barrel makers list 1:12 as standard for the 375.....

Seems like we beat this around long ago, and the consensus was: Don't bother with anything besides 1 in 12" twist. It is fast enough twist for 300 grain monometals and 350 grain lead cored bullets, and does the job on all lighter bullets in a hunting rifle. What special application would require anything different?

1 in 12" twist will handle all the bullets made for the 375 H&H round! A 1 in 11" might be better for the 350 gr bullet now available, but the 1 in 12" will still do for hunting, and that's what a 375 H&H is for!