On one of the Ruger forums I look at, there was a message that there will be a limited number of No. 1's chambered for the .375 Ruger. Not sure which configuration, that was all that was said.

im willing to bet on the tropical number 1

I'll stick with my #1H in 375 H&H. Since the #1 doesn't have any limitations on cartridge length, there would be no advantage to chambering it for the new 375. It would be done simply for marketing purposes or for Ruger collectors. To my mind the only problem the new round addresses is that it allows one to get 375 H&H performance in a standard length bolt action. Lou